Wayne Beach, Ph.D.
College of Professional Studies and Fine Arts
School of Communication
Dr. Wayne Beach is Professor in the School of Communication at SDSU, Adjunct Professor, Department of Surgery, and Member of the Moores UCSD Cancer Center, University of California, San Diego. His research and teaching focus on the convergence of conversational and institutional interaction.
He has pioneered diverse studies focusing on the social organization of verbal and embodied features of everyday talk and action. A particular concern with health and illness has given rise to long-term investigations of how family members talk through cancer on the telephone, medical interviewing in primary, preventive, and oncological care, and related illness dilemmas (e.g., bulimia, obesity, chest pain, cancer diagnosis, treatment, and prognosis).
Samuel Shen, Ph.D.
College of Sciences
Department of Mathematics and Statistics
Dr. Shen is Distinguished Professor of Mathematics and Statistics at San Diego State University and Visiting Research Mathematician at Scripps Institution of Oceanography, UCSD. He received his B.Sc. in Engineering Mechanics in 1982 from the Nanjing University of Science and Technology, and his M.A. and Ph.D. in Applied Mathematics from the University of Wisconsin-Madison in 1985 and 1987, respectively. Formerly, Dr. Shen was McCalla Professor of Mathematical and Statistical Sciences at the University of Alberta, Canada, and President of the Canadian Applied and Industrial Mathematics Society. He also held a variety of visiting positions at NASA Goddard Space Flight Center, US Climate Prediction Center, and University of Tokyo.
Manal A. Swairjo, Ph.D.
College of Sciences
Department of Chemistry & Biochemistry
My research focuses on tRNA biogenesis processes and their links to human disease. tRNA is an ancient molecule that evolved to be the adapter between amino acids and codons, thus mediating the translation of the genetic code. The coding properties of tRNA do not reside only in its primary sequence.
Post-transcriptional nucleoside modification, particularly in the anticodon-stem loop (ASL) region of tRNA, are required for cognate and/or wobble codon recognition and translocation, they enhance aminoacylation properties of tRNA, and prevent ribosomal frameshifting.
Deficiencies in tRNA modifications cause a variety of diseases, e.g. hereditary human mitochondrial disease, and modified nucleosides serve as sensitive human cancer markers. Most significantly, modifications of the anticodon-stem loop have been implicated in viral replication as several retroviruses rely on modifications of host cell tRNA for virulence or to replicate.