ADMINISTRATIVE SUPPLEMENT

Childhood Cancer LEAP4AHEAD

logo for Leap Ahead website

SDSU Principal Investigators                     UCSD Principal Investigators

Elizabeth A. Klonoff, Ph.D.                                         Ana M. Navarro, Ph.D.

Stanley R. Maloy, Ph.D.                                             John M. Carethers, M.D.

Abstract

Each year, cancer kills more children between 1 and 20 years of age than asthma, diabetes, cystic fibrosis, and AIDS combined.  Though more than 80% of children with cancer will survive, a majority of survivors will experience late effects.  Late effects refer to disabilities or other adverse outcomes as a result of the disease, its treatment, or both.  Late effects include neuro-cognitive, cardiac, endocrine, and reproductive disorders, obesity, bone issues, secondary cancers, and psychosocial difficulties.  Late effects programs for screening and counseling are valuable resources; however, growing numbers of survivors may lack access to the extremely limited number of programs.  Thus, development of other resources designed to increase awareness of early detection, treatment, and amelioration of pediatric cancers’ late effects could have a large public health impact.  There is also a void in the public’s awareness of pediatric cancers and late effects in children, adolescents, and young adults.  Thus, the purpose of this descriptive study is to create an innovative, interactive, Web-based program (along with printed materials) for the general public, survivors, families, and professionals about the risks, detection, treatments, and prevention of late effects of childhood cancer.  A coalition of representatives from the Partnership’s existing organizations and new collaborations will assist in developing the content, pilot-testing, refining, and translating web-based and written materials to make them culturally and linguistically competent.  Community partners will be engaged to promote the messages and to assess its public impact.  LEAP AHEAD will serve as a tool to disseminate knowledge to the public about late effects of cancer and ensure that pediatric cancer survivors of diverse groups are aware of necessary long-term medical and psychological care.

Project Period: 9/1/2010 – 8/31/2013

NCI Grants #U54 CA132384 and #U54 CA132379